Our research explores how redox-active metal complexes interact with biological systems and how these interactions can be harnessed to address major challenges in human disease. A central focus of the laboratory is the development of redox-active, light-activated metal chromophores for cancer photomedicine, particularly strategies designed to overcome tumor hypoxia and improve therapeutic response. We investigate the photochemical, redox, and biological mechanisms that govern the activity of these systems and use this knowledge to design next-generation metal-based therapeutics. In parallel, we study metallocofactors in viral proteins to understand how transition metals regulate biological function and disease. By integrating synthesis, spectroscopy, imaging, and biological studies, we seek to establish new principles for metal-based therapeutics, photomedicine, and molecular medicine.